منابع مشابه
Degradation of Methyldopa by Banana
Methyldopa, an antihypertensive, is a very close analogue of DOPA. Drug interaction accompanied by degradation in a banana juice mixture was reported for DOPA. However, the effect of banana on methyldopa has not been reported. Therefore, we have investigated the impact of banana juice on methyldopa. The drug and supernatant of banana pulp were mixed, and the mixture was observed for changes in ...
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a rise in serum alkaline phosphatase, glutamic oxaloacetic transaminase levels, and increased Bromsulphalein retention. Elevation of the serum bilirubin may occur. In its most benign form the condition is usually symptomless, but complaints, such as anorexia, abdominal pain, or pruritus, and signs, such as fever or hepatomegaly, may occur. Histologic changes similar to those of viral hepatitis ...
متن کاملAmenorrhoea, galactorrhoea, and hyperprolactinaemia induced by methyldopa.
Meacock SCR, Kitchen EA, Dawson W. Effects of benoxaprofen and some other non-steroidal anti-inflammatory drugs on leucocyte migration. European J'ournal of Rheumatology and Inflammation 1979 ;3 :23. 2 Collum LMT, Bowen DI. Ocular side effects of ibuprofen. BrJ' Ophthalmol 1971;55:472-7. 3 Palmer CAL. Toxic amblyopia from ibuprofen. Br MedJ 1972;iii:765. 4 Melluish JW, Brooks CD, Ruoff G, Cross...
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15 صفحه اولAntihypertensive Metabolites of a-Methyldopa
a-Methyldopa acts through a metabolite in the central nervous system. Of the three metabolites most prominently considered as potential mediators of a-methyldopa hypotension — amethyldopamine, a-methylnorepinephrine (MNE), and a-methylepinephrine (ME) — ME is the most potent depressor agent following intravenous infusion into rats, following injection into the lateral ventricle, and following i...
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ژورنال
عنوان ژورنال: Pharmaceuticals
سال: 2010
ISSN: 1424-8247
DOI: 10.3390/ph3030441